This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This Mouse Dnmt3l antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 383-417 amino acids from the C-terminal region of Mouse Dnmt3l.
TRDMT1
Reactivity: Human
WB, ELISA, IHC, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB: 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Target
DNMT3L (TRDMT1)
(DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
Alternative Name
Dnmt3l
Background
Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases.