EHD2 antibody (C-Term)

Catalog No. ABIN6243197

This Rabbit Polyclonal antibody specifically detects EHD2 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for EHD2 antibody (C-Term) (ABIN6243197)

Target: EHD2 (EH-Domain Containing 2 (EHD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EHD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB51848

Product Details anti-EHD2 Antibody

Binding Specificity: AA 415-449, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EHD2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 415-449 amino acids from the C-terminal region of human EHD2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:500-1:2000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for EHD2

Target: EHD2 (EH-Domain Containing 2 (EHD2))

Alternative Name: EHD2

Background: Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Required for translocation of FER1L5 to the plasma membrane. Binds ATP, does not bind GTP (By similarity).

Molecular Weight: 61161

UniProt: Q9NZN4

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development