SEMA4D/CD100 antibody (C-Term)

Catalog No. ABIN6243520

The Rabbit Polyclonal anti-SEMA4D/CD100 antibody (Clone RB52931) (ABIN6243520) specifically detects SEMA4D/CD100 in WB. The antibody is reactive with Human samples.

Quick Overview for SEMA4D/CD100 antibody (C-Term) (ABIN6243520)

Target: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEMA4D/CD100 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB52931

Product Details anti-SEMA4D/CD100 Antibody

Binding Specificity: AA 793-832, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SEMA4D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 793-832 amino acids from the C-terminal region of human SEMA4D.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SEMA4D/CD100

Target: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Alternative Name: SEMA4D

Background: Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system, induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.

Molecular Weight: 96150

UniProt: Q92854

Pathways: Regulation of Cell Size