MAGI3 antibody (AA 1330-1360)

Catalog No. ABIN6243878

This Rabbit Polyclonal antibody specifically detects MAGI3 in WB. It exhibits reactivity toward Human.

Quick Overview for MAGI3 antibody (AA 1330-1360) (ABIN6243878)

Target: MAGI3 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 3 (MAGI3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGI3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB53923

Product Details anti-MAGI3 Antibody

Binding Specificity: AA 1330-1360

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MAGI3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1330-1360 amino acids from human MAGI3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for MAGI3

Target: MAGI3 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 3 (MAGI3))

Alternative Name: MAGI3

Background: Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.

Molecular Weight: 162949

UniProt: Q5TCQ9