NDN antibody (N-Term)

Catalog No. ABIN6243906

The Rabbit Polyclonal anti-NDN antibody has been validated for WB. It is suitable to detect NDN in samples from Human.

Quick Overview for NDN antibody (N-Term) (ABIN6243906)

Target: NDN (Necdin Homolog (Mouse) (NDN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDN antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB51025

Product Details anti-NDN Antibody

Binding Specificity: AA 75-109, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NDN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 75-109 amino acids from the N-terminal region of human NDN.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for NDN

Target: NDN (Necdin Homolog (Mouse) (NDN))

Alternative Name: NDN

Background: Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle- promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).

Molecular Weight: 36086

UniProt: Q99608

Pathways: Neurotrophin Signaling Pathway