DKK2 antibody

Catalog No. ABIN6244156

Product Details anti-DKK2 Antibody

Target: DKK2 (Dickkopf 2 Homolog (DKK2))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This DKK2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This DKK2 antibody is generated from a mouse immunized with a recombinant protein of human DKK2.

Clone: 1833CT856-7-20

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for DKK2

Target: DKK2 (Dickkopf 2 Homolog (DKK2))

Alternative Name: DKK2 (DKK2 Products)

Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Molecular Weight: 28447

UniProt: Q9UBU2

Pathways: WNT Signaling