EPO antibody

Catalog No. ABIN6252344

This anti-EPO antibody is a Mouse Monoclonal antibody detecting EPO in WB, FACS, IF and IHC (p). Suitable for Human.

Quick Overview for EPO antibody (ABIN6252344)

Target: EPO (Erythropoietin (EPO))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPO antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: EPO-1367

Product Details anti-EPO Antibody

Purification: Protein G affinity chromatography

Immunogen: A human partial recombinant protein was used as the immunogen for the Erythropoietin antibody.

Isotype: IgG

Application Details

Application Notes: IF: 1-2 μg/mL

Immunohistochemistry (FFPE): 4-8 μg/mL for 30 min at RT

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Titering of the Erythropoietin antibody may be required for optimal performance.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for EPO

Target: EPO (Erythropoietin (EPO))

Alternative Name: Erythropoietin

Target Type: Hormone

Background: Erythropoietin / EPO is a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. It is the primary factor responsible for regulating erythropoiesis during steady-state conditions and in response to blood loss and hemorrhage in the adult organism. Erythropoietin is synthesized by the kidney and stimulates the proliferation and maturation of bone marrow erythroid precursor cells. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis.

Gene ID: 2056

UniProt: P01588

Pathways: JAK-STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity