Quick Overview for CD45RO antibody (FITC) (ABIN6253060)
Target
CD45RO
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Conjugate
This CD45RO antibody is conjugated to FITC
Application
Flow Cytometry (FACS)
Grade
GMP Grade
Clone
UCHL1
Purpose
CD45RO FITC Antibody
Characteristics
The clone UCHL1 recognizes 180-185 KD surface antigen known as CD45RO commonly expressed by thymocytes, a subset of resting, memory and activated T cells, activated monocytes/macrophages, granulocytes and myeloma cells. CD45RO is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. It plays important rule in development of lymphocytes and antigen signaling, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.