CD40 antibody (PE)

Catalog No. ABIN6253103

The PE-conjugated Mouse Monoclonal anti-CD40 antibody (Clone G28-5) (ABIN6253103) specifically detects CD40 in FACS. The antibody is reactive with Human, Cynomolgus, Baboon and Rhesus Monkey samples.

Quick Overview for CD40 antibody (PE) (ABIN6253103)

Target: CD40

Reactivity: Human, Cynomolgus, Baboon, Rhesus Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD40 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: G28-5

Product Details anti-CD40 Antibody (PE)

Purpose: CD40 PE Antibody

Characteristics: The clone G28-5 is specific for CD40 B cell surface antigen. It is a 48 kD type I glycoprotein and a member of the tumor necrosis factor receptor superfamily. CD40 is the receptor for CD40 ligand (CD40L), a molecule predominantly expressed by activated CD4+ T cells. The CD40 on B cells and CD40L (CD154) on activated helper T cells are co-stimulatory molecules whose interaction is required for the proliferation and immunoglobulin (Ig) class switching of antigen-activated B cells.

Purification: Purified

Purity: >95 %

Immunogen: Human tonsillar lymphocytes

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for CD40

Target: CD40

Alternative Name: CD40

UniProt: P25942

Pathways: NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints