CD44 antibody (FITC)

Catalog No. ABIN6253896

This anti-CD44 antibody is a Mouse Monoclonal antibody detecting CD44 in FACS. Suitable for Human.

Quick Overview for CD44 antibody (FITC) (ABIN6253896)

Target: CD44

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD44 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: MEM-85

Product Details anti-CD44 Antibody (FITC)

Specificity: MEM-85 produces mouse IgG2b immunoglobulins directed against the human 85 kD human adhesion receptor

Isotype: IgG2b

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C

Target Details for CD44

Target: CD44

Alternative Name: CD44

Background: Antigen distribution: CD44, otherwise known as the lymphocyte homing receptor, is widely expressed on hematopoietic and non-hematopoietic cells. It is found especially on epithelial, endothelial, mesothelial and mesenchymal cells as well as in the nervous system. The major isoform is CD44H which is expressed on lymphoid, myeloid and erythroid cells. Expression is increased on activated and memory/effector T cells. Soluble forms of CD44 can be detected in body fluids [1,2]. MEM-85 was clustered at the Leukocyte Typing Workshop IV [3,4]. Cellular Expression: Epithelial, endothelial, mesothelial and mesenchymal cells.

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling