Transferrin Receptor antibody

Catalog No. ABIN6253931

This anti-Transferrin Receptor antibody is a Mouse Monoclonal antibody detecting Transferrin Receptor in FACS and ICC. Suitable for Human.

Quick Overview for Transferrin Receptor antibody (ABIN6253931)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: DF1513

Product Details anti-Transferrin Receptor Antibody

Specificity: DF1513, produces mouse IgG1 immunoglobulins directed against the transferrin receptor. The transferrin receptor is a type II membrane glycoprotein existing as a homodimer of 180-190 kD with the interchain disulphide bond

Purification: Ion exchange column

Purity: PURE

Isotype: IgG1

Application Details

Application Notes: immunohistochemistry on cytospots, immunohistochemistry on paraffin imbedded, immunohistochemistry on frozen tissue sections

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: CD71

Background: Antigen distribution: Expression of CD71, or the transferrin receptor, is very low on resting leukocytes but is upregulated upon activation reflecting the iron dependence of activation. In other tissues, CD71 is expressed on most dividing cells and also on brain endothelium and alveolar macrophage [1,2]. The ligand is the serum iron transport protein transferrin. DF1513 was clustered at the Leukocyte Typing Workshop IV [5]. Cellular Expression: Activated leukocytes.

Pathways: Transition Metal Ion Homeostasis