CD163 antibody (PE)

Catalog No. ABIN6253945

This Mouse Monoclonal antibody specifically detects CD163 in WB, FACS, ELISA, ICC and FM. It exhibits reactivity toward Human.

Quick Overview for CD163 antibody (PE) (ABIN6253945)

Target: CD163

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD163 antibody is conjugated to PE

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Fluorescence Microscopy (FM)

Clone: MAC2-158

Product Details anti-CD163 Antibody (PE)

Specificity: The CD163 antigen is the cysteine-rich human scavenger receptor protein (p155, M130) found on mononuclear phagocytes, monocytes, and macrophages. CD163 is up-regulated on mononuclear phagocytes by IL-4, IL-6 and dexamethasone and serves as a receptor for the hemoglobin / haptoglobin complex. Expression of CD163 is restricted to cells of monocyte lineage and increases as the monocytes mature into macrophages. CD163 is present on all CD14 + monocytes, most CD64+ monocytes, and demonstrates higher expression on CD16+ monocytes. Stimulation of monocytes and macrophages by lipopolysacharide (LPS), IL-10, and tumor necrosis factor alpha (TNF-α) causes shedding of CD163 from the cell surface into plasma or supernata

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C

Target Details for CD163

Target: CD163

Alternative Name: CD163

Background: Antigen distribution: The CD163 antigen is the cysteine-rich human scavenger receptor protein (p155, M130) found on mononuclear phagocytes, monocytes, and macrophages. CD163 is up-regulated on mononuclear phagocytes by IL-4, IL-6 and dexamethasone and serves as a receptor for the hemoglobin / haptoglobin complex. Expression of CD163 is restricted to cells of monocyte lineage and increases as the monocytes mature into macrophages. CD163 is present on all CD14 + monocytes, most CD64+ monocytes, and demonstrates higher expression on CD16+ monocytes. Stimulation of monocytes and macrophages by lipopolysacharide (LPS), IL-10, and tumor necrosis factor alpha (TNF-α) causes shedding of CD163 from the cell surface into plasma or supernata. Cellular Expression: Mononuclear phagocytes, monocytes and macrophages.