MEF2C antibody (pSer222)

Catalog No. ABIN6254109

The Rabbit Polyclonal anti-MEF2C antibody has been validated for WB. It is suitable to detect MEF2C in samples from Human. There is 1 publication available.

Quick Overview for MEF2C antibody (pSer222) (ABIN6254109)

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MEF2C Antibody

Binding Specificity: pSer222

Cross-Reactivity: Human

Predicted Reactivity: bovine, chicken, guinea pig, mouse, non-human primate, rat, sheep

Purification: Antigen Affinity Purified from Pooled Serum

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser222 conjugated to KLH

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

References for anti-MEF2C antibody (ABIN6254109)

Brown, Still, Koche, Yim, Takao, Cifani, Reed, Gunasekera, Ficarro, Romanienko, Mark, McCarthy, de Stanchina, Gonen, Seshan, Bhola, ODonnell, Spitzer, Stutzke, Lavallée, Hébert, Krivtsov, Melnick et al.: "MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia. ..." in: Cancer discovery, Vol. 8, Issue 4, pp. 478-497, (2019) (PubMed).

Target Details for MEF2C

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Alternative Name: MEF2C

Molecular Weight: '51 kDa

Gene ID: 4208

UniProt: Q06413

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling