MEF2C antibody (pSer222)

Catalog No. ABIN6254109

The Rabbit Polyclonal anti-MEF2C antibody has been validated for WB and ELISA. It is suitable to detect MEF2C in samples from Human. There is 1 publication available.

Quick Overview for MEF2C antibody (pSer222) (ABIN6254109)

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2C antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MEF2C Antibody

Binding Specificity: pSer222

Specificity: Specific for endogenous levels of the ~51 kDa MEF2C protein phosphorylated at Ser222. Immunolabeling is completely eliminated by treatment with λ-phosphatase.

Cross-Reactivity: Human

Predicted Reactivity: bovine, chicken, guinea pig, mouse, non-human primate, rat, sheep

Characteristics: Our MEF2C (Ser222) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects MEF2C (Ser222) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser222 of human MEF2C, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes:

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Expiry Date: 12 months

References for anti-MEF2C antibody (ABIN6254109)

Brown, Still, Koche, Yim, Takao, Cifani, Reed, Gunasekera, Ficarro, Romanienko, Mark, McCarthy, de Stanchina, Gonen, Seshan, Bhola, ODonnell, Spitzer, Stutzke, Lavallée, Hébert, Krivtsov, Melnick et al.: "MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia. ..." in: Cancer discovery, Vol. 8, Issue 4, pp. 478-497, (2019) (PubMed).

Target Details for MEF2C

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Alternative Name: MEF2C

Background:

Synonyms: C5DELq14.3 antibody, DEL5q14.3 antibody, MADS box transcription enhancer factor 2 polypeptide C (myocyte enhancer factor 2C) antibody, MADS box transcription enhancer factor 2 polypeptide C antibody, MEF2C antibody, MEF2C_HUMAN antibody, Myocyte enhancer factor 2C antibody, Myocyte specific enhancer factor 2C antibody, Myocyte-specific enhancer factor 2C antibody, OTTHUMP00000222409 antibody, Similar to MADS box transcription enhancer factor 2 polypeptide C antibody

Description Logic: Our MEF2C (Ser222) rabbit polyclonal phosphospecific primary antibody is produced . It detects MEF2C (Ser222) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: MEF2C

Molecular Weight: 51 kDa

Gene ID: 4208

UniProt: Q06413

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling