C-Peptide antibody
Quick Overview for C-Peptide antibody (ABIN6254201)
Target
See all C-Peptide AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Sequence
- EAEDLQVGQV ELGGGPGAGS LQPLALEGSL QGT-EVEDPQVAQL ELGGGPGAGD LQTLALEVAR Q
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Specificity
- Detects C-peptide using MBP-C-peptide recombinant fusion protein and GFP-C-peptide expressed in transfected mammalian cells.
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Characteristics
- pro-insulin
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Purification
- This antibody is epitope-affinity purified from goat antiserum.
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Immunogen
- Purified recombinant human and rat C-peptides produced in E. coli as a fusion protein.
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2,000
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Restrictions
- For Research Use only
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Concentration
- 4.00 mg/mL
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Buffer
- Polyclonal antibody supplied as a 200 µl (4 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide.
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Handling Advice
- The antibody solution should be gently mixed before use.
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Storage
- 4 °C,-20 °C
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Storage Comment
- For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.
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- C-Peptide
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Background
- C-Peptide is part of proinsulin, that consists of C-Peptide, alpha and beta chains that later become linked together to form the insulin molecule. Each proinsulin molecule produces one molecule of insulin and one molecule of C-peptide that is released into the blood. C-peptide stimulates the N+, K+ -ATPase and endothelial nitric oxide synthase activities by binding to cell membranes which leads to increased intracellular Ca2+ concentration.
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Gene ID
- 3630
Target
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