CD31 antibody (C-Term)

Catalog No. ABIN6254202

Cited in 1 publication. The Goat Polyclonal anti-CD31 antibody (ABIN6254202) specifically detects CD31 in WB, IHC (p) and IHC (fro). The antibody is reactive with Human, Mouse, Rat, Rabbit, Pig, Cow, Dog, Monkey, Sheep, Hamster, Goat, Avian, Cat, Chicken, Donkey, Guinea Pig and Horse samples.

Quick Overview for CD31 antibody (C-Term) (ABIN6254202)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivity: Human, Mouse, Rat, Rabbit, Pig, Cow, Dog, Monkey, Sheep, Hamster, Goat, Avian, Cat, Chicken, Donkey, Guinea Pig, Horse

Host: Goat

Clonality: Polyclonal

Conjugate: This CD31 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CD31 Antibody

Binding Specificity: C-Term

Purpose: Anti-CD31

Sequence: TEVQVSSAES HKDLGKKDTE TVYSEVRKAV PDAVESRYSR TEGSLDGT

Specificity: Using PBM cell lysates detects a 130-140 kDa band by Western blot.

Characteristics: Platelet/endothelial Cell Adhesion Molecule (PECAM1)

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptide within residues 690 aa to the C-terminus of human CD31 produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000

Restrictions: For Research Use only

Handling

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

References for anti-CD31 antibody (ABIN6254202)

Rodrigues, Matafome, Sereno, Almeida, Castelhano, Gamas, Neves, Gonçalves, Carvalho, Arslanagic, Wilcken, Fonseca, Simões, Conde, Castelo-Branco, Seiça: "Methylglyoxal-induced glycation changes adipose tissue vascular architecture, flow and expansion, leading to insulin resistance." in: Scientific reports, Vol. 7, Issue 1, pp. 1698, (2018) (PubMed).

Target Details for CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Alternative Name: CD31

Background:

Goat polyclonal antibody to CD31. CD31 is a 130-140 kDa type I transmembrane glycoprotein. It is expressed in platelets, granulocytes, stem cells of myeloid lineage, monocytes and endothelial cells. It is likely to be involved in integrin activation, leukocyte migration and angiogenesis.

CD31/endoCAM, endoCAM, PECA1, PECAM1, PECAM-1, platelet/endothelial adhesion molecule 1 antibody.

Molecular Weight: 130-140 kDa,140 kDa

Pathways: Regulation of Actin Filament Polymerization