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Histone H4 antibody (acLys5)

Reactivity: Human, Mouse, Rat WB, IHC, IF, ELISA, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6254903
  • Target See all Histone H4 Antibodies
    Histone H4
    Binding Specificity
    • 27
    • 26
    • 24
    • 18
    • 18
    • 15
    • 14
    • 14
    • 14
    • 13
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    acLys5
    Reactivity
    • 285
    • 220
    • 217
    • 15
    • 14
    • 10
    • 9
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Human, Mouse, Rat
    Host
    • 306
    • 22
    • 2
    Rabbit
    Clonality
    • 279
    • 49
    • 2
    Polyclonal
    Conjugate
    • 169
    • 20
    • 14
    • 14
    • 14
    • 14
    • 14
    • 14
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    This Histone H4 antibody is un-conjugated
    Application
    • 157
    • 86
    • 74
    • 72
    • 37
    • 37
    • 36
    • 32
    • 32
    • 29
    • 29
    • 22
    • 15
    • 10
    • 9
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
    Specificity
    Acetyl-Histone H4 (Lys5) Antibody detects endogenous levels of Acetyl-Histone H4 only when phosphorylated at Lys5
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    Immunogen affinity purified
    Immunogen
    A synthesized peptide derived from human Acetyl-Histone H4 around the phosphorylation site of Lys5
    Isotype
    IgG
    Top Product
    Discover our top product Histone H4 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Hu, Chang, Yan, Rong, Yang, Cheng, Gu, Yao, Hou, Mo, Zhao, Chen, Dinlin, Wang, Fang: "(-)-Epigallocatechin-3-gallate induces cancer cell apoptosis via acetylation of amyloid precursor protein." in: Medical oncology (Northwood, London, England), Vol. 32, Issue 1, pp. 390, (2016) (PubMed).

  • Target
    Histone H4
    Abstract
    Histone H4 Products
    Background

    Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Gene: HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4

    Molecular Weight
    11kDa
    Gene ID
    121, 504, 554
    UniProt
    P62805
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