STAT5 A/B antibody (pSer725, pSer730)

Catalog No. ABIN6256413

The Rabbit Polyclonal anti-STAT5 A/B antibody has been validated for WB, ELISA, IHC, IF and ICC. It is suitable to detect STAT5 A/B in samples from Human, Mouse and Rat.

Quick Overview for STAT5 A/B antibody (pSer725, pSer730) (ABIN6256413)

Target: STAT5 A/B

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT5 A/B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-STAT5 A/B Antibody

Binding Specificity: pSer725, pSer730

Specificity: Phospho-STAT5A/B (Ser725/730) Antibody detects endogenous levels of STAT5A/B only when phosphorylated at Serine 725/730

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human STAT5A/B around the phosphorylation site of Serine 725/730

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for STAT5 A/B

Target: STAT5 A/B

Alternative Name: STAT5A/B

Background:

Description: Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.

Gene: STAT5A

Molecular Weight: 90kDa

Gene ID: 6776

UniProt: P42229, P51692