Ezrin antibody (pTyr146)
Quick Overview for Ezrin antibody (pTyr146) (ABIN6256643)
Target
See all Ezrin (EZR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pTyr146
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Specificity
- Phospho-Ezrin (Tyr146) Antibody detects endogenous levels of Ezrin only when phosphorylated at Tyrosine 146.
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Predicted Reactivity
- Pig,Horse,Rabbit,Dog
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Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human Ezrin around the phosphorylation site of Tyr146.
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
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Expiry Date
- 12 months
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- Ezrin (EZR)
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Alternative Name
- EZR
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Background
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Description: Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Gene: EZR
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Molecular Weight
- 69kDa
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Gene ID
- 7430
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UniProt
- P15311
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Pathways
- Maintenance of Protein Location
Target
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