Integrin alpha 1 antibody (Internal Region)

Catalog No. ABIN6257047

This anti-Integrin alpha 1 antibody is a Rabbit Polyclonal antibody detecting Integrin alpha 1 in WB, ELISA, ICC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for Integrin alpha 1 antibody (Internal Region) (ABIN6257047)

Target: Integrin alpha 1 (ITGA1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin alpha 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-Integrin alpha 1 Antibody

Binding Specificity: Internal Region

Specificity: ITGA1 Antibody detects endogenous levels of total ITGA1.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ITGA1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for Integrin alpha 1

Target: Integrin alpha 1 (ITGA1)

Alternative Name: ITGA1

Background:

Description: Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth.

Gene: ITGA1

Molecular Weight: 131 kDa

Gene ID: 3672

UniProt: P56199

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex