CLDN8 antibody (C-Term)

Catalog No. ABIN6257106

The Rabbit Polyclonal anti-CLDN8 antibody has been validated for ELISA, WB, IF and ICC. It is suitable to detect CLDN8 in samples from Human.

Quick Overview for CLDN8 antibody (C-Term) (ABIN6257106)

Target: CLDN8 (Claudin 8 (CLDN8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLDN8 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-CLDN8 Antibody

Binding Specificity: C-Term

Specificity: Claudin 8 Antibody detects endogenous levels of total Claudin 8.

Predicted Reactivity: Bovine,Horse,Sheep,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Claudin 8, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CLDN8

Target: CLDN8 (Claudin 8 (CLDN8))

Alternative Name: CLDN8

Background:

Description: Tight-junction protein required for paracellular chloride transport in the kidney. Mediates recruitment of CLDN4 to tight junction in the kidney. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Gene: CLDN8

Molecular Weight: 28 kDa

Gene ID: 9073

UniProt: P56748

Pathways: Hepatitis C