FGF12 antibody (C-Term)

Catalog No. ABIN6257178

The Rabbit Polyclonal anti-FGF12 antibody is suitable to detect FGF12 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for FGF12 antibody (C-Term) (ABIN6257178)

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-FGF12 Antibody

Binding Specificity: C-Term

Specificity: FGF12 Antibody detects endogenous levels of total FGF12.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FGF12, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for FGF12

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Alternative Name: FGF12

Background:

Description: Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation.

Gene: FGF12

Molecular Weight: 27 kDa

Gene ID: 2257

UniProt: P61328

Pathways: Negative Regulation of Transporter Activity