GRID2 antibody (C-Term)

Catalog No. ABIN6257247

The Rabbit Polyclonal anti-GRID2 antibody has been validated for WB, IF, ELISA, IHC and ICC. It is suitable to detect GRID2 in samples from Human, Rat and Mouse.

Quick Overview for GRID2 antibody (C-Term) (ABIN6257247)

Target: GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRID2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-GRID2 Antibody

Binding Specificity: C-Term

Specificity: GRID2 Antibody detects endogenous levels of total GRID2.

Predicted Reactivity: Pig,Zebrafish,Sheep,Rabbit,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GRID2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GRID2

Target: GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

Alternative Name: GRID2

Background:

Description: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Promotes synaptogenesis and mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis of cerebellar parallel fiber-Purkinje cell (PF-PC) synapses through the beta-NRX1-CBLN1-GRID2 triad complex (PubMed:27418511).

Gene: GRID2

Molecular Weight: 113 kDa

Gene ID: 2895

UniProt: O43424

Pathways: Synaptic Membrane