RIOK2 antibody (Internal Region)

Catalog No. ABIN6257460

The Rabbit Polyclonal anti-RIOK2 antibody has been validated for WB, ELISA, IF, IHC and ICC. It is suitable to detect RIOK2 in samples from Human.

Quick Overview for RIOK2 antibody (Internal Region) (ABIN6257460)

Target: RIOK2 (RIO Kinase 2 (RIOK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIOK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-RIOK2 Antibody

Binding Specificity: Internal Region

Specificity: RIOK2 Antibody detects endogenous levels of total RIOK2.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RIOK2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for RIOK2

Target: RIOK2 (RIO Kinase 2 (RIOK2))

Alternative Name: RIOK2

Background:

Description: Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA (PubMed:19564402). Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function (PubMed:21880710).

Gene: RIOK2

Molecular Weight: 63 kDa

Gene ID: 55781

UniProt: Q9BVS4