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RIOK2 antibody (Internal Region)

The Rabbit Polyclonal anti-RIOK2 antibody has been validated for WB, ELISA, IF, IHC and ICC. It is suitable to detect RIOK2 in samples from Human.
Catalog No. ABIN6257460
$494.77
Plus shipping costs $50.00
Shipping to: United States
Delivery in 11 to 12 Business Days

Quick Overview for RIOK2 antibody (Internal Region) (ABIN6257460)

Target

See all RIOK2 Antibodies
RIOK2 (RIO Kinase 2 (RIOK2))

Reactivity

  • 44
  • 4
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  • 3
  • 3
  • 3
  • 3
  • 2
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  • 1
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Human

Host

  • 38
  • 6
Rabbit

Clonality

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Polyclonal

Conjugate

  • 25
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
This RIOK2 antibody is un-conjugated

Application

  • 32
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  • 6
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  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • Binding Specificity

    • 7
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    • 1
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    Internal Region

    Specificity

    RIOK2 Antibody detects endogenous levels of total RIOK2.

    Purification

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    Immunogen

    A synthesized peptide derived from human RIOK2, corresponding to a region within the internal amino acids.

    Isotype

    IgG
  • Application Notes

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Expiry Date

    12 months
  • Target

    RIOK2 (RIO Kinase 2 (RIOK2))

    Alternative Name

    RIOK2

    Background

    Description: Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA (PubMed:19564402). Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function (PubMed:21880710).

    Gene: RIOK2

    Molecular Weight

    63 kDa

    Gene ID

    55781

    UniProt

    Q9BVS4
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