TTC19 antibody (Internal Region)

Catalog No. ABIN6257537

This Rabbit Polyclonal antibody specifically detects TTC19 in ELISA, WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TTC19 antibody (Internal Region) (ABIN6257537)

Target: TTC19 (Tetratricopeptide Repeat Domain 19 (TTC19))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTC19 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TTC19 Antibody

Binding Specificity: Internal Region

Specificity: TTC19 Antibody detects endogenous levels of total TTC19.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TTC19, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for TTC19

Target: TTC19 (Tetratricopeptide Repeat Domain 19 (TTC19))

Alternative Name: TTC19

Background:

Description: Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1 (PubMed:21278747, PubMed:28673544). Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation of UQCRFS1 into the complex III and whose presence is detrimental for its catalytic activity (PubMed:28673544).

Gene: TTC19

Molecular Weight: 35 kDa

Gene ID: 54902

UniProt: Q6DKK2