IL17RD antibody (C-Term)

Catalog No. ABIN6257609

This Rabbit Polyclonal antibody specifically detects IL17RD in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for IL17RD antibody (C-Term) (ABIN6257609)

Target: IL17RD (Interleukin 17 Receptor D (IL17RD))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RD antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL17RD Antibody

Binding Specificity: C-Term

Specificity: IL17RD Antibody detects endogenous levels of total IL17RD.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IL17RD, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for IL17RD

Target: IL17RD (Interleukin 17 Receptor D (IL17RD))

Alternative Name: IL17RD

Background:

Description: Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons (By similarity).

Gene: IL17RD

Molecular Weight: 80 kDa

Gene ID: 54756

UniProt: Q8NFM7

Pathways: Toll-Like Receptors Cascades