Unc5c antibody (N-Term)

Catalog No. ABIN6257656

This anti-Unc5c antibody is a Rabbit Polyclonal antibody detecting Unc5c in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Unc5c antibody (N-Term) (ABIN6257656)

Target: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Unc5c antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Unc5c Antibody

Binding Specificity: N-Term

Specificity: UNC5C Antibody detects endogenous levels of total UNC5C.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human UNC5C, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for Unc5c

Target: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Alternative Name: UNC5C

Background:

Description: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.

Gene: UNC5C

Molecular Weight: 66 kDa

Gene ID: 8633

UniProt: O95185