ING2 antibody (C-Term)

Catalog No. ABIN6257713

This anti-ING2 antibody is a Rabbit Polyclonal antibody detecting ING2 in WB, ELISA, IF and ICC. Suitable for Human and Mouse.

Quick Overview for ING2 antibody (C-Term) (ABIN6257713)

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-ING2 Antibody

Binding Specificity: C-Term

Specificity: ING2 Antibody detects endogenous levels of total ING2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ING2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for ING2

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Alternative Name: ING2

Background:

Description: Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).

Gene: ING2

Molecular Weight: 33 kDa

Gene ID: 3622

UniProt: Q9H160

Pathways: Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling