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HSD11B1 antibody (Hydroxysteroid (11-Beta) Dehydrogenase 1) Primary Antibody

HSD11B1 Reactivity: Human, Mouse, Rat ELISA, ICC, IF, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257907
$390.77
Plus shipping costs $45.00
100 μL ABIN6257907
100 μL ABIN6257907
local_shipping Shipping to: United States
Delivery in 8 to 9 Business Days
  • Target
    HSD11B1
    Reactivity
    • 57
    • 30
    • 25
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 48
    • 14
    • 4
    Rabbit
    Clonality
    • 57
    • 9
    Polyclonal
    Conjugate
    • 33
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HSD11B1 antibody is un-conjugated
    Application
    • 46
    • 30
    • 15
    • 9
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
    Specificity
    HSD11B1 Antibody detects endogenous levels of total HSD11B1
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide
    Isotype
    IgG
  • Application Notes
    WB 1:500~1:1000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    HSD11B1
    Alternative Name
    HSD11B1 (HSD11B1 Antibody Abstract)
    Synonyms
    11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1, hsd11, hsd11b, LRRGT00065, hydroxysteroid 11-beta dehydrogenase 1, hydroxysteroid (11-beta) dehydrogenase 1b, hydroxysteroid (11-beta) dehydrogenase 1 L homeolog, HSD11B1, HSD11B1b, hsd11b1.L, Hsd11b1
    Background

    Description: Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity).

    Gene: HSD11B1

    Molecular Weight
    32 kDa
    Gene ID
    3290
    UniProt
    P28845
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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