GPR68 antibody (Internal Region)

Catalog No. ABIN6258203

This Rabbit Polyclonal antibody specifically detects GPR68 in WB, ELISA, IF and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for GPR68 antibody (Internal Region) (ABIN6258203)

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR68 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-GPR68 Antibody

Binding Specificity: Internal Region

Specificity: OGR1/GPR68 Antibody detects endogenous levels of total OGR1/GPR68.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human OGR1/GPR68, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for GPR68

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Alternative Name: GPR68

Background:

Description: Proton-sensing receptor involved in  pH homeostasis. May represents an osteoblastic  pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at  pH 7.8 but fully activated at  pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity).

Gene: GPR68

Molecular Weight: 41 kDa

Gene ID: 8111

UniProt: Q15743