GPR62 antibody (C-Term)
Quick Overview for GPR62 antibody (C-Term) (ABIN6258284)
Target
See all GPR62 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- GPR62 Antibody detects endogenous levels of total GPR62.
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Predicted Reactivity
- Horse
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human GPR62, corresponding to a region within C-terminal amino acids.
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Expiry Date
- 12 months
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- GPR62 (G Protein-Coupled Receptor 62 (GPR62))
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Alternative Name
- GPR62
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Background
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Description: Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways (PubMed:28827538). Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538). Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538).
Gene: GPR62
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Molecular Weight
- 38 kDa
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Gene ID
- 118442
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UniProt
- Q9BZJ7
Target
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