TRAF4 antibody (Internal Region)

Catalog No. ABIN6258339

The Rabbit Polyclonal anti-TRAF4 antibody has been validated for WB, ELISA, IF and ICC. It is suitable to detect TRAF4 in samples from Human, Mouse and Rat.

Quick Overview for TRAF4 antibody (Internal Region) (ABIN6258339)

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-TRAF4 Antibody

Binding Specificity: Internal Region

Specificity: TRAF4 Antibody detects endogenous levels of total TRAF4.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TRAF4, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TRAF4

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Alternative Name: TRAF4

Background:

Description: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.

Gene: TRAF4

Molecular Weight: 53 kDa

Gene ID: 9618

UniProt: Q9BUZ4