CCNB1IP1 antibody (Internal Region)

Catalog No. ABIN6258548

This Rabbit Polyclonal antibody specifically detects CCNB1IP1 in WB, ELISA, ICC and IF. It exhibits reactivity toward Human.

Quick Overview for CCNB1IP1 antibody (Internal Region) (ABIN6258548)

Target: CCNB1IP1 (Cyclin B1 Interacting Protein 1 (CCNB1IP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCNB1IP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-CCNB1IP1 Antibody

Binding Specificity: Internal Region

Specificity: CCNB1IP1 Antibody detects endogenous levels of total CCNB1IP1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CCNB1IP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CCNB1IP1

Target: CCNB1IP1 (Cyclin B1 Interacting Protein 1 (CCNB1IP1))

Alternative Name: CCNB1IP1

Background:

Description: Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL-gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.

Gene: CCNB1IP1

Molecular Weight: 32 kDa

Gene ID: 57820

UniProt: Q9NPC3