AGBL4 antibody (C-Term)

Catalog No. ABIN6258702

The Rabbit Polyclonal anti-AGBL4 antibody has been validated for WB, ELISA, ICC and IF. It is suitable to detect AGBL4 in samples from Human.

Quick Overview for AGBL4 antibody (C-Term) (ABIN6258702)

Target: AGBL4 (ATP/GTP Binding Protein-Like 4 (AGBL4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGBL4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-AGBL4 Antibody

Binding Specificity: C-Term

Specificity: AGBL4 Antibody detects endogenous levels of total AGBL4.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AGBL4, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for AGBL4

Target: AGBL4 (ATP/GTP Binding Protein-Like 4 (AGBL4))

Alternative Name: AGBL4

Background:

Description: Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.

Gene: AGBL4

Molecular Weight: 62 kDa

Gene ID: 84871

UniProt: Q5VU57