GPRC6A antibody (Internal Region)

Catalog No. ABIN6258833

This Rabbit Polyclonal antibody specifically detects GPRC6A in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for GPRC6A antibody (Internal Region) (ABIN6258833)

Target: GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPRC6A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-GPRC6A Antibody

Binding Specificity: Internal Region

Specificity: GPRC6A Antibody detects endogenous levels of total GPRC6A.

Predicted Reactivity: Pig,Bovine,Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GPRC6A, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GPRC6A

Target: GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))

Alternative Name: GPRC6A

Background:

Description: Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca2+ and Mg2+. Activated by extracellular calcium and osteocalcin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids.

Gene: GPRC6A

Molecular Weight: 105 kDa

Gene ID: 222545

UniProt: Q5T6X5