RAB7L1 antibody (Internal Region)

Catalog No. ABIN6259170

The Rabbit Polyclonal anti-RAB7L1 antibody has been validated for WB, ELISA, ICC and IF. It is suitable to detect RAB7L1 in samples from Human, Mouse and Rat.

Quick Overview for RAB7L1 antibody (Internal Region) (ABIN6259170)

Target: RAB7L1 (RAB7, Member RAS Oncogene Family-Like 1 (RAB7L1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB7L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-RAB7L1 Antibody

Binding Specificity: Internal Region

Specificity: RAB7L1 Antibody detects endogenous levels of total RAB7L1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RAB7L1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for RAB7L1

Target: RAB7L1 (RAB7, Member RAS Oncogene Family-Like 1 (RAB7L1))

Alternative Name: RAB29

Background:

Description: Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection.

Gene: RAB29

Molecular Weight: 28 kDa

Gene ID: 8934

UniProt: O14966