FIL1d antibody (Internal Region)

Catalog No. ABIN6259266

The Rabbit Polyclonal anti-FIL1d antibody has been validated for WB, ELISA, ICC and IF. It is suitable to detect FIL1d in samples from Human and Mouse.

Quick Overview for FIL1d antibody (Internal Region) (ABIN6259266)

Target: FIL1d (Interleukin 1 delta (FIL1d))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FIL1d antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-FIL1d Antibody

Binding Specificity: Internal Region

Specificity: IL1F5 Antibody detects endogenous levels of total IL1F5.

Predicted Reactivity: Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IL1F5, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for FIL1d

Target: FIL1d (Interleukin 1 delta (FIL1d))

Alternative Name: IL36RN

Background:

Description: Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response, similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Gene: IL36RN

Molecular Weight: 17 kDa

Gene ID: 26525

UniProt: Q9UBH0