ALKBH4 antibody (Internal Region)

Catalog No. ABIN6259501

This anti-ALKBH4 antibody is a Rabbit Polyclonal antibody detecting ALKBH4 in WB, ELISA, IF and ICC. Suitable for Human and Mouse.

Quick Overview for ALKBH4 antibody (Internal Region) (ABIN6259501)

Target: ALKBH4 (AlkB, Alkylation Repair Homolog 4 (E. Coli) (ALKBH4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALKBH4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-ALKBH4 Antibody

Binding Specificity: Internal Region

Specificity: ALKBH4 Antibody detects endogenous levels of total ALKBH4.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ALKBH4, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for ALKBH4

Target: ALKBH4 (AlkB, Alkylation Repair Homolog 4 (E. Coli) (ALKBH4))

Alternative Name: ALKBH4

Background:

Description: Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.

Gene: ALKBH4

Molecular Weight: 36 kDa

Gene ID: 54784

UniProt: Q9NXW9