APOBR antibody (C-Term)

Catalog No. ABIN6259983

The Rabbit Polyclonal anti-APOBR antibody has been validated for WB and ELISA. It is suitable to detect APOBR in samples from Human.

Quick Overview for APOBR antibody (C-Term) (ABIN6259983)

Target: APOBR (Apolipoprotein B Receptor (APOBR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOBR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-APOBR Antibody

Binding Specificity: C-Term

Specificity: APOB48R Antibody detects endogenous levels of total APOB48R.

Predicted Reactivity: Pig,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human APOB48R, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for APOBR

Target: APOBR (Apolipoprotein B Receptor (APOBR))

Alternative Name: APOBR

Background:

Description: Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.

Gene: APOBR

Molecular Weight: 115 kDa

Gene ID: 55911

UniProt: Q0VD83