ACER1 antibody (Internal Region)

Catalog No. ABIN6260068

This anti-ACER1 antibody is a Rabbit Polyclonal antibody detecting ACER1 in WB, ELISA, IHC, ICC and IF. Suitable for Human, Rat and Mouse.

Quick Overview for ACER1 antibody (Internal Region) (ABIN6260068)

Target: ACER1 (Alkaline Ceramidase 1 (ACER1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACER1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-ACER1 Antibody

Binding Specificity: Internal Region

Specificity: ASAH3 Antibody detects endogenous levels of total ASAH3.

Predicted Reactivity: Pig,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ASAH3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ACER1

Target: ACER1 (Alkaline Ceramidase 1 (ACER1))

Alternative Name: ACER1

Background:

Description: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal  pH of 8.0. Has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. May have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids (By similarity).

Gene: ACER1

Molecular Weight: 31 kDa

Gene ID: 125981

UniProt: Q8TDN7