AXIN2 antibody (N-Term)

Catalog No. ABIN6260163

The Rabbit Polyclonal anti-AXIN2 antibody is suitable to detect AXIN2 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for AXIN2 antibody (N-Term) (ABIN6260163)

Target: AXIN2 (Axin 2 (AXIN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AXIN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-AXIN2 Antibody

Binding Specificity: N-Term

Specificity: AXIN2 Antibody detects endogenous levels of total AXIN2.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AXIN2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for AXIN2

Target: AXIN2 (Axin 2 (AXIN2))

Alternative Name: AXIN2

Background:

Description: Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B (By similarity).

Gene: AXIN2

Molecular Weight: 93kDa

Gene ID: 8313

UniProt: Q9Y2T1

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling