Caprin-1 antibody (Internal Region)

Catalog No. ABIN6260454

The Rabbit Polyclonal anti-Caprin-1 antibody has been validated for WB, IHC, IF and ICC. It is suitable to detect Caprin-1 in samples from Human, Rat and Mouse.

Quick Overview for Caprin-1 antibody (Internal Region) (ABIN6260454)

Target: Caprin-1 (Cell Cycle Associated Protein 1 (Caprin-1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caprin-1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-Caprin-1 Antibody

Binding Specificity: Internal Region

Specificity: CAPRIN1 Antibody detects endogenous levels of total CAPRIN1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CAPRIN1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Caprin-1

Target: Caprin-1 (Cell Cycle Associated Protein 1 (Caprin-1))

Alternative Name: CAPRIN1

Background:

Description: May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.

Gene: CAPRIN1

Molecular Weight: 116kDa

Gene ID: 4076

UniProt: Q14444