CCL19 antibody (N-Term)

Catalog No. ABIN6260539

This anti-CCL19 antibody is a Rabbit Polyclonal antibody detecting CCL19 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for CCL19 antibody (N-Term) (ABIN6260539)

Target: CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL19 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCL19 Antibody

Binding Specificity: N-Term

Specificity: CCL19 Antibody detects endogenous levels of total CCL19.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CCL19, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CCL19

Target: CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

Alternative Name: CCL19

Background:

Description: May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

Gene: CCL19

Molecular Weight: 11kDa

Gene ID: 6363

UniProt: Q99731

Pathways: Positive Regulation of Immune Effector Process