AGTPBP1 antibody (Internal Region)

Catalog No. ABIN6260553

The Rabbit Polyclonal anti-AGTPBP1 antibody is suitable to detect AGTPBP1 in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for AGTPBP1 antibody (Internal Region) (ABIN6260553)

Target: AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGTPBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-AGTPBP1 Antibody

Binding Specificity: Internal Region

Specificity: CCP1 Antibody detects endogenous levels of total CCP1.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CCP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for AGTPBP1

Target: AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))

Alternative Name: AGTPBP1

Background:

Description: Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.

Gene: AGTPBP1

Molecular Weight: 138 kDa

Gene ID: 23287

UniProt: Q9UPW5

Pathways: Proton Transport