CEP164 antibody (C-Term)

Catalog No. ABIN6260765

This Rabbit Polyclonal antibody specifically detects CEP164 in WB and IHC. It exhibits reactivity toward Human, Rat and Dog.

Quick Overview for CEP164 antibody (C-Term) (ABIN6260765)

Target: CEP164 (Centrosomal Protein 164kDa (CEP164))

Reactivity: Human, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP164 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CEP164 Antibody

Binding Specificity: C-Term

Specificity: CEP164 Antibody detects endogenous levels of total CEP164.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CEP164, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CEP164

Target: CEP164 (Centrosomal Protein 164kDa (CEP164))

Alternative Name: CEP164

Background:

Description: Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1.

Gene: CEP164

Molecular Weight: 164 kDa

Gene ID: 22897

UniProt: Q9UPV0

Pathways: M Phase