CMTM4 antibody (N-Term)

Catalog No. ABIN6260904

The Rabbit Polyclonal anti-CMTM4 antibody has been validated for ELISA, WB, ICC and IF. It is suitable to detect CMTM4 in samples from Human.

Quick Overview for CMTM4 antibody (N-Term) (ABIN6260904)

Target: CMTM4 (CKLF-Like MARVEL Transmembrane Domain Containing 4 (CMTM4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CMTM4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-CMTM4 Antibody

Binding Specificity: N-Term

Specificity: CMTM4 Antibody detects endogenous levels of total CMTM4.

Predicted Reactivity: Pig,Zebrafish,Bovine,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CMTM4, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CMTM4

Target: CMTM4 (CKLF-Like MARVEL Transmembrane Domain Containing 4 (CMTM4))

Alternative Name: CMTM4

Background:

Description: Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. May protect PD-L1/CD274 from being polyubiquitinated and targeted for degradation.

Gene: CMTM4

Molecular Weight: 25kDa

Gene ID: 146223

UniProt: Q8IZR5