D Amino Acid Oxidase antibody (C-Term)

Catalog No. ABIN6261219

The Rabbit Polyclonal anti-D Amino Acid Oxidase antibody has been validated for WB, ELISA and IHC. It is suitable to detect D Amino Acid Oxidase in samples from Human, Mouse and Rat. There is 1 publication available.

Quick Overview for D Amino Acid Oxidase antibody (C-Term) (ABIN6261219)

Target: D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This D Amino Acid Oxidase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-D Amino Acid Oxidase Antibody

Binding Specificity: C-Term

Specificity: DAO Antibody detects endogenous levels of total DAO.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DAO, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

References for anti-D Amino Acid Oxidase antibody (ABIN6261219)

Zhang, Yang, Wang, Wang, Liu, Yin, Ye: "Decreased Endogenous Hydrogen Sulfide Generation in Penile Tissues of Diabetic Rats with Erectile Dysfunction." in: The journal of sexual medicine, Vol. 13, Issue 3, pp. 350-60, (2016) (PubMed).

Target Details for D Amino Acid Oxidase

Target: D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))

Alternative Name: DAO

Background:

Description: Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.

Gene: DAO

Molecular Weight: 39kDa

Gene ID: 1610

UniProt: P14920