DENND4A antibody (Internal Region)

Catalog No. ABIN6261270

The Rabbit Polyclonal anti-DENND4A antibody has been validated for WB and ELISA. It is suitable to detect DENND4A in samples from Human and Mouse.

Quick Overview for DENND4A antibody (Internal Region) (ABIN6261270)

Target: DENND4A (DENN/MADD Domain Containing 4A (DENND4A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DENND4A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DENND4A Antibody

Binding Specificity: Internal Region

Specificity: DENND4A Antibody detects endogenous levels of total DENND4A.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DENND4A, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DENND4A

Target: DENND4A (DENN/MADD Domain Containing 4A (DENND4A))

Alternative Name: DENND4A

Background:

Description: Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.

Gene: DENND4A

Molecular Weight: 209kDa

Gene ID: 10260

UniProt: Q7Z401