FOXH1 antibody (Internal Region)

Catalog No. ABIN6261789

The Rabbit Polyclonal anti-FOXH1 antibody has been validated for WB, ELISA, IF and ICC. It is suitable to detect FOXH1 in samples from Human and Mouse.

Quick Overview for FOXH1 antibody (Internal Region) (ABIN6261789)

Target: FOXH1 (Forkhead Box H1 (FOXH1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-FOXH1 Antibody

Binding Specificity: Internal Region

Specificity: FOXH1 Antibody detects endogenous levels of total FOXH1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FOXH1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: IF/ICC 1:100-1:500, WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for FOXH1

Target: FOXH1 (Forkhead Box H1 (FOXH1))

Alternative Name: FOXH1

Background:

Description: Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).

Gene: FOXH1

Molecular Weight: 40kDa

Gene ID: 8928

UniProt: O75593

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling