Histone 3 antibody (H3K14me, H3K14me2, H3K14me3)
-
- Target See all Histone 3 (H3) Antibodies
- Histone 3 (H3)
-
Binding Specificity
- H3K14me, H3K14me2, H3K14me3
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Histone 3 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
- Specificity
- Histone H3 (mono+di+tri methyl K14) Antibody detects endogenous levels of total Histone H3 (mono+di+tri methyl K14)
- Cross-Reactivity
- Human, Mouse (Murine)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Histone H3 (mono+di+tri methyl K14)
- Isotype
- IgG
- Top Product
- Discover our top product H3 Primary Antibody
-
-
- Application Notes
- WB 1:1000-3000 ICC/IF
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
-
- Target
- Histone 3 (H3)
- Alternative Name
- Histone H3 (H3 Products)
- Background
-
Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J
- Molecular Weight
- 15kDa
- Gene ID
- 8, 350, 835
- UniProt
- P68431, P84243, Q16695
-