LETM1 antibody (Internal Region)
Quick Overview for LETM1 antibody (Internal Region) (ABIN6262951)
Target
See all LETM1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- Internal Region
-
Specificity
- LETM1 Antibody detects endogenous levels of total LETM1.
-
Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
-
Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
Immunogen
- A synthesized peptide derived from human LETM1, corresponding to a region within the internal amino acids.
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Expiry Date
- 12 months
-
-
- LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))
-
Alternative Name
- LETM1
-
Background
-
Description: Mitochondrial proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion (PubMed:19797662). Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain (PubMed:18628306). Required for the maintenance of the tubular shape and cristae organization (PubMed:18628306). In contrast to SLC8B1/NCLX, does not constitute the major factor for mitochondrial calcium extrusion (PubMed:24898248).
Gene: LETM1
-
Molecular Weight
- 83 kDa
-
Gene ID
- 3954
-
UniProt
- O95202
Target
-